Stomach ulcer or peptic ulcer have become common for those people who are living in urban areas of a developing country. It generally develops due to the destruction of intestinal mucosal lining of the stomach by Hydrochloric acid present in the digestive juices of the stomach. Helicobacter Pyroli, a microbe, is responsible for causing both gastric and duodenal ulcer which can be treated and eliminated by the use of antibiotics and acid suppressants. In few cases stomach ulcer or peptic ulcer is seems to be developed due to over-dosage of aspirin and other nonsteroidal antiinflammatory drugs.
As per the latest research, childhood H. pylori infection has been associated to malnutrition, growth impairment, and other health related ailments. In this regards, scientists have come up with an idea of special yogurt which is more economical and suggest a more convenient way to deal with these bacteria. There are many artificial remedy available in the market that may have some side effects, therefore scientist have opted for a natural way of treating stomach ulcer i.e. through producing special yogurt.
Scientists have also conducted first human clinical trial in order to prove that new yogurt is capable of inhibiting the growth of bacteria that causes gastritis and stomach ulcers and also, it has vaccine-like effects, scientists at 237th National Meeting of the American Chemical Society. Researchers were aware of the fact that yogurt, a fermented milk product constitute live bacteria, is a source of protein, calcium, and other necessary nutrients. Therefore they though implementing a research on yogurt can not only provide solution for peptic ulcer, but can also deal with nutrition deficiency. At present there are many brands available in the market which contain “Probiotics”- a special type of bacteria capable to improving health condition, as main constituent. This special yogurt not only fights with the stomach ulcers, but also contribute a major part of growing “functional food” market in US and is generating $60 billion in sales annually.
“With the large scale production of this yogurt, more and more people can enjoy the taste as well as they can prevent or eliminate the bacteria that causes peptic ulcer or stomach ulcer,” said Hajime Hatta, Ph.D., a chemist at Kyoto Women’s University in Kyoto, Japan. This special yogurt is already been marketed in Japan, Korea, Taiwan and seems to enter into US market soon. Also, Hatta and his colleagues pointed out that H. pylori rely on a protein, urease, to get attached to and infect the inner lining of the stomach. In order to prevent the protein, or an antigen, Hatta switched to a classic vaccine-making technology.
They injected urease into the chicken and made chickens’ immune system to produce an antibody for the protein. Thereafter researcher harvested antibody, with so called IgY-urease, from chicken eggs. Hatta with his colleagues concluded that yogurt with antibody in it may be helpful in preventing bacteria from adhering the stomach lining.
In order to prove peptic ulcer healing effect of yogurt, scientist selected 42 volunteer with positive H. pylori infection. These volunteer were divided into two groups, one as control group and other as yogurt antibody group. Control group was given plain yogurt while antibody yogurt group was fed with yogurt containing antibody for four weeks. After four weeks, it was observed that the levels of urea, a byproduct of urease, has come down significantly in antibody group when compared with control group, showing reduced bacterial activity. The result obtained after conducting the test indicates that H. Pylori infection in human can be prevented by consuming yogurt fortified with urease antibody, Hatta said. Initially it was observed that antibody was destroyed by stomach acid, but not before having its beneficial effects.
Hatta commented, thought yogurt with antibody is less effective than those antibiotics available in medical store to treat H. pylori infection, yet is suggested as because it can be easily included in regular diet and can also provide basic nutrients to those suffering from nutrition deficiency. The presence of antibody does not change the taste of yogurt at all and also it does not have any harmful side effect.
Hatta also pointed out that, antibody yogurt is not for everyone. He seriously cautioned to people who are allergic to milk, eggs, and other diary products and directed to avoid this yogurt product. Though yogurt is made up of egg yolk, which is expected to have less allergen levels than egg white, but still there is a risk of getting allergic attack, he concluded.